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the differences in bup

Discussion in 'Detoxing From Buprenorphine/Subutex/Suboxone' started by kevin, Jan 14, 2004.

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  1. kevin

    kevin Guest

    Is it possible to have an allergic reaction to the naloxone in the subuxone even though it's inert unless IVed?

    Also, is it possible subuxone is easier to come off of than subutex? I've heard that a couple of times. Again, there shouldn't be a difference, should there be?


    Thanks...
     
  2. pinkie

    pinkie Well-Known Member

    My doc laughed at the idea that the nal in Suboxone made any difference unless injected. I personally never had a blip of a problem with it, nor did I have an issue with swallowing saliva, but some would argue. Ah, the many mysteries of my love.
     
  3. Rodrigo

    Rodrigo Well-Known Member

    Doubtful... But consult rxlist.com and look up suboxone. I know even tho the bioavailability of naloxone sublingually is next to nothing, I remember seeing that a trace amount is absorbed into the system. How long have you been on sub and what are your allergy symptoms?
     
  4. kevin

    kevin Active Member

    No, not me, I've been reading about alergy symtoms. I couldn't understand how this would be possible. There's so much confusion around these drugs, it's amazing.
     
  5. Rodrigo

    Rodrigo Well-Known Member

    Well, once again, it is *supposed* to have no effect at all. Here's a quote on suboxone: "Physiologic and subjective effects following acute sublingual administration of SUBOXONE and SUBUTEX tablets were similar at equivalent dose levels of buprenorphine. Naloxone, in the SUBOXONE formulation, had no clinically significant effect when administered by the sublingual route, although blood levels of the drug were measurable." Since there are measurable blood levels of naloxone, I would say that it *is* possible to have an allergy to it. You're right -- it's confusing as hell to me, hence why I avoided it for my detox. [}:)]
     
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