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Thread: Baclofen

  1. #1
    trust4me is offline Senior Member
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    Default Baclofen

    Hi Guys,

    Has anyone ever heard of Baclofen being used for opiate addiction? I've read that it's being used to successfully treat alcoholism, and I was wondering if it is also being used to treat other drug addictions?

    Thanks.
    Last edited by jdude; 04-27-2011 at 03:06 PM.

  2. #2
    inneedofhelp is offline Senior Member
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    Default Re: Baclofen

    I take it for my back problems It's like a muscle relaxant. I've never heard it being used as a treatment for addiction, though
    Where did you find this information?

    Are you on or coming off of anything else?

    Good Luck to you

  3. #3
    Catamount's Avatar
    Catamount is offline Senior Member
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    Default Re: Baclofen

    What I found:

    Dr. Olivier Ameisen, a French-American associate professor of medicine and a cardiologist at Weill Cornell Medical College of Cornell University, reported in 2004 in the journal Alcohol and Alcoholism that he successfully used Baclofen to completely suppress his own alcohol addiction. In his paper, he called for randomized trials of high-dose baclofen to be conducted to test the therapeutic model he had proposed. He renewed his call for clinical trials in the Journal of the American Medical Association (JAMA). His therapeutic model was reproduced by Dr. William Bucknam, who published a case report in Alcohol and Alcoholism, and by Roberta Agabio et al. who published another case in Journal of Clinical Psychopharmacology. Ameisen believes, based on his own experience and other anecdotal evidence, that Baclofen acts on some mechanism within the brains of addicts to suppress cravings brought on by addiction to various substances such as alcohol, cocaine, and heroin.
    Ameisen, who currently is a visiting professor of medicine at State University of New York Downstate Medical Center, authored Le Dernier Verre (The Last Glass, titled The End of My Addiction in English) to inform public opinion and physicians.[12][13] Since his book has been released, hundreds of patients have been treated in academic centers and rapidly become "indifferent to alcohol".[citation needed] Also, clinical trials are being mounted as a result of public pressure.[citation needed]
    Recently, based on Ameisen's therapeutic model, some trials have been conducted in using Baclofen to treat cocaine addiction. In 2007, an Italian team has demonstrated the effectiveness and the safety of baclofen as a treatment for alcohol-addiction[5] People have said once they took Baclofen they felt their desire for cocaine plummet almost overnight.[citation needed] There is also a report that baclofen has beneficial role in the management of reflux disease.[14]
    Cheers.....living it 1 day at a time and loving it!
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  4. #4
    Joplinfrk's Avatar
    Joplinfrk is offline Senior Member
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    Default Re: Baclofen

    The best thing for withdrawals: just take it one minute at a time. Don't put more crap into your already poisoned body. There is no magic bullet or free pass of the opiate express..this is the price we pay for abusing pills. The great news is that it's short and small in the great scheme of things. Focus on staying clean so you never have to feel like crap again.
    Don't be afraid of withdrawal. The sick feeling will pass and then the real work starts: staying sober. For me, the rooms of AA were the last thing I tried and the first thing that worked, but it will only work if you work it.

    1/31/2008

  5. #5
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    Default Re: Baclofen

    Quote Originally Posted by Joplinfrk View Post
    The best thing for withdrawals: just take it one minute at a time. Don't put more crap into your already poisoned body. There is no magic bullet or free pass of the opiate express..this is the price we pay for abusing pills. The great news is that it's short and small in the great scheme of things. Focus on staying clean so you never have to feel like crap again.
    She said it so well. There is no majic bullet, if there was we we would know and we would have less addicts.

    I fell most people who are addicted remain addicted due to the fear of withdrawl.

  6. #6
    kunzite52 is offline Senior Member
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    Default Re: Baclofen

    the big ? for all addicts is "What will I do then?" What will I do when the withdrawals set in? After withdrawals are over how will I live without drugs? How can I attend meetings when I do not believe in everything they say? The answer is always the same, you do one thing at a time. One day at a time, and yeah for awhile it will be one moment at a time.
    Addiction can do all sorts of things to the mind and body, and there is only ONE thing that keeps you doing it over and over. What is that one ONE thing? It is fear. And that That is what you must overcome. And as you do it, as each day goes by the fear will lessen with each one you face, and so time will pass, one day at a time, and so that is WHAT you will do then.
    All the best my dear!
    With respect,
    I ask you to try to be that willing,
    annie
    Last edited by jdude; 04-27-2011 at 03:06 PM.
    Anne

  7. #7
    Joplinfrk's Avatar
    Joplinfrk is offline Senior Member
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    Default Re: Baclofen

    You are absolutely right, TOBS. It's the FEAR of withdrawal that keeps us spinning that vicious cycle. We hate pain, any pain.
    When I first cleaned up, you bet I didn't know what to do with myself. Now, I fill my time with meetings, helping new people in recovery, writing...I'm learning to live again. He'll, I had to learn to everything all over again, sober. Once upon a time, I had to get high to get out of bed; I was a slave to the pills. Imagine that: something the size of a fingernail controlling us!!
    Nah...no more for me. All I have is today.
    Don't be afraid of withdrawal. The sick feeling will pass and then the real work starts: staying sober. For me, the rooms of AA were the last thing I tried and the first thing that worked, but it will only work if you work it.

    1/31/2008

  8. #8
    jdude's Avatar
    jdude is offline Senior Member
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    Default Re: Baclofen

    To answer your question, the clinical trials that were proposed (havn't followed it for a while now) were to replace meds for RLS and rebound pain associated with WDs. Some of the standard current protocols are hard on the liver.

    Would kinda make sense...on paper anyways. But at this point would be scripted way 'off label'...for detoxing.

    Jay
    Last edited by jdude; 04-27-2011 at 03:06 PM.
    You can't solve problems by using the same kind of thinking that caused them in the first place.

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    Default Re: Baclofen

    Withdrawal syndrome
    Discontinuation of baclofen can be associated with a withdrawal syndrome which resembles benzo and alcohol withdrawal. Withdrawal symptomsare more likely if baclofen is used for long periods of time (more than a couple of months) and can occur from low or high doses. The severity of baclofen withdrawal depends on the rate at which baclofen is discontinued. Thus to minimise baclofen withdrawal symptoms the dose should be tapered down slowly when discontinuing baclofen therapy. Abrupt withdrawal is most likely to result in severe withdrawal symptoms. Acute withdrawal symptoms can be stopped by recommencing baclofen.
    Withdrawal symptoms may include auditory hallucinations, visual hallucinations, tactile hallucinations, delusions, confusion, agitation, delerium, disorientation, fluctuation of consciousness,insomnia, inattention, memory impairments, perceptual disturbances, anxiety, depersonalization, hypertonia, hyperthermia, formal thought disorder, psychosis, mania, mood disturbances, restlessness, and behavioral disturbances, tachycardia, seizures, tremors, autonomic dysfunction, hyperpyrexia, extreme muscle rigidity resembling neuroleptic malignant syndrome and rebound spasticity.
    Last edited by spring; 07-20-2010 at 11:54 AM.

  10. #10
    Amarok is offline Junior Member
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    Default Re: Baclofen

    There is a book by Dr Ameisen about Baclofen: The End of My Addiction. I think Baclofen is useful for withdrawal, and extremely useful for maintenance of sobriety: it obviates cravings and desire to use for many different substances, alcohol, opiates, cocaine. It is not something that can be abused, as long as it is tapered, there is nothing like the benzo withdrawal. I believe it is extremely helpful, and if it helps in the recovery process, fantastic. For purists who feel that any substance should be avoided, that's fine as a personal view for yourself, but others should have the opportunity to try it. If you've had a relapse or relapses, this could be key in helping you stay clean. From personal experience, the desire to use is just. not. there.

  11. #11
    Friend2U is offline Senior Member
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    Default Re: Baclofen

    Amarok
    I find it interesting that the two posts on baclofen are opposite. Are you still taking the baclofen? Can you tell me your story about baclofen in your life?

  12. #12
    jdude's Avatar
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    Default Re: Baclofen

    Quote Originally Posted by Amarok View Post
    There is a book by Dr Ameisen about Baclofen: The End of My Addiction. I think Baclofen is useful for withdrawal, and extremely useful for maintenance of sobriety: it obviates cravings and desire to use for many different substances, alcohol, opiates, cocaine. It is not something that can be abused, as long as it is tapered, there is nothing like the benzo withdrawal. I believe it is extremely helpful, and if it helps in the recovery process, fantastic. For purists who feel that any substance should be avoided, that's fine as a personal view for yourself, but others should have the opportunity to try it. If you've had a relapse or relapses, this could be key in helping you stay clean. From personal experience, the desire to use is just. not. there.
    Key Phrase..."There is a book..."
    You can't solve problems by using the same kind of thinking that caused them in the first place.

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