Results 1 to 11 of 11
  1. #1
    Cincinnati Kid is offline Junior Member
    Join Date
    Oct 2010
    Posts
    9

    Default Imodium (loperamide) interesting facts!

    Long ago, during one of the many WD's I've endured, I began to suspect that Loperamide was doing more for me than relieveing my diarrhea. I knew that it had at least one quality similar to opioids in that it decreased intestinal activity, but I also seemed to feel just slightly better overall after taking it. Now, years later I'm taking Loperamide again for my Suboxone WD's and am noticing the same thing. I skipped the Imodium the past two days and felt a lot worse yesterday. Today I felt mediocre. A couple of hours ago I took an Imodium tablet and now I at least feel able to get through the rest of the day. Now, click on this link Loperamide - Wikipedia, the free encyclopedia and read the first line under the paragraph titled Mechanism. It says that Loperamide is an "opioid agonist"...it later says that it only acts on the bowel region...but I dunno...why do I feel just a bit better overall after taking it? Has anyone else here noticed that Imodium seems to "take the edge off" of the WD's?

  2. #2
    jdude's Avatar
    jdude is offline Senior Member
    Join Date
    Mar 2007
    Location
    Foothills of SC
    Posts
    6,779

    Default Re: Imodium (loperamide) interesting facts!

    If you put Imodium in the search function, you'll come up with about 11 pages(800+) of recent posts regarding Imodium.

    Yes, it's an opiate base, but doesn't cross the blood brain barrier.
    You can't solve problems by using the same kind of thinking that caused them in the first place.

  3. #3
    Parachute is offline Senior Member
    Join Date
    Feb 2008
    Location
    , , .
    Posts
    3,622

    Default Re: Imodium (loperamide) interesting facts!

    In the sixties they treated the WD of Heroin Addicts with Loperamide. Yep, it helps.
    PEACE

  4. #4
    Cincinnati Kid is offline Junior Member
    Join Date
    Oct 2010
    Posts
    9

    Default Re: Imodium (loperamide) interesting facts!

    Thanks Jdude and parachute. "They" say it does not cross the blood-brain barrier, but we all have opioid receptors elsewhere...like along the spine. If one reads the article to the end, it mentions WD's resulting in mice given large doses of Loperamide for a long period. Is it possible "they" aren't telling us all the information? I mean, come on...we weren't told the truth about Suboxone, why should we trust what the Establishment tells us about Loperamide? I think it gives relief beyond the loose bowels...so despite the blood-brain issue, I think people should decide for themselves whether or not it gives extra relief.

  5. #5
    Parachute is offline Senior Member
    Join Date
    Feb 2008
    Location
    , , .
    Posts
    3,622

    Default Re: Imodium (loperamide) interesting facts!

    It is unquestionable that it gives relief over and above just the bathroom issues. I leaned on it HARD in cold turkey jump from a huge oxy habit...No doubt it helped with some of the symptoms, beyond any question at all.
    PEACE

  6. #6
    jdude's Avatar
    jdude is offline Senior Member
    Join Date
    Mar 2007
    Location
    Foothills of SC
    Posts
    6,779

    Default Re: Imodium (loperamide) interesting facts!

    Quote Originally Posted by Cincinnati Kid View Post
    If one reads the article to the end, it mentions WD's resulting in mice given large doses of Loperamide for a long period.
    But were the mice addicts wanting recovery? :p And how long were they on suboxone?

    Using anything in small doses..short term, doesn't compare to large doses for a non warranted time period. Of which a warning of duration of use is on the box..even the generics.
    You can't solve problems by using the same kind of thinking that caused them in the first place.

  7. #7
    Sluggo's Avatar
    Sluggo is offline Senior Member
    Join Date
    Jan 2007
    Location
    NJ
    Posts
    4,890

    Default Re: Imodium (loperamide) interesting facts!

    Did the mice have sponsors? Did they work any steps at all during detox?

  8. #8
    tenn_smoothie's Avatar
    tenn_smoothie is offline Senior Member
    Join Date
    Jul 2006
    Location
    tennessee
    Posts
    596

    Default Re: Imodium (loperamide) interesting facts!

    i used the prescription loperamide this summer during my taper and didn't notice any effect on my withdrawal level at all - i was disappointed because i had been told the stuff would help beyond the intestinal issues as well.

  9. #9
    jdude's Avatar
    jdude is offline Senior Member
    Join Date
    Mar 2007
    Location
    Foothills of SC
    Posts
    6,779

    Default Re: Imodium (loperamide) interesting facts!

    Quote Originally Posted by tenn_smoothie View Post
    i used the prescription loperamide this summer during my taper and didn't notice any effect on my withdrawal level at all - i was disappointed because i had been told the stuff would help beyond the intestinal issues as well.
    Hey Rich...not sure what script you were given. But too frequently docs script the Lomotil (Diphenoxylate). Unlike the loperamide, it dose cross the brain-blood barrier. And the sub will block it as an opiate agonist.
    You can't solve problems by using the same kind of thinking that caused them in the first place.

  10. #10
    tenn_smoothie's Avatar
    tenn_smoothie is offline Senior Member
    Join Date
    Jul 2006
    Location
    tennessee
    Posts
    596

    Default Re: Imodium (loperamide) interesting facts!

    Quote Originally Posted by jdude View Post
    Hey Rich...not sure what script you were given. But too frequently docs script the Lomotil (Diphenoxylate). Unlike the loperamide, it dose cross the brain-blood barrier. And the sub will block it as an opiate agonist.
    ahhhh, so that was the problem.

    thx for the correction J - it was, in fact, a Lomotil script, not loperamide.

  11. #11
    jdude's Avatar
    jdude is offline Senior Member
    Join Date
    Mar 2007
    Location
    Foothills of SC
    Posts
    6,779

    Default Re: Imodium (loperamide) interesting facts!

    There's really no 'correction'. On one of the Apollo missions an astronaut had some 'issues'...and used Lomotil. A NASA spokesman coined it 'prescription Imodium'...been called that ever since.

    It's very effective for the gastro issues...but should be used very short term.
    Some docs will even script the tramadols for it. But neither is a good choice in detox mode...especially from sub.

    If dehydration and or diarrhea is an issue in IP,(detox mode) most will go with a loperamide or loperamide/phenergan combo. The phenergan will potentiate the loperamide.

    And not to confuse the issue, but in the UK loperamide can be mixed with codiene under another trade name...and needs a script.
    You can't solve problems by using the same kind of thinking that caused them in the first place.

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •  
Information in this forum is not monitored or provided by a medical professional. The information reflects member opinions only. Do not act on advice from these forums without first consulting a qualified medical professional. All content is copyrighted and protected by Aelius Group.